Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 8/20 | 0.50 |
| ▸ | HTR2B | P41595 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154700 | 0.83 | GPR84 (0.58) | HTR2CHTR2AHTR2BGAAKDM4E | |
| SCHEMBL9651757 | 0.80 | HTR2C (0.56) | HTR2CHTR2AHTR2BGAAKDM4E | |
| SCHEMBL29450053 | 0.80 | HTR2C (0.56) | HTR2CHTR2AHTR2BGAAKDM4E | |
| SCHEMBL29764387 | 0.80 | GPR84 (0.64) | HTR2AGAAGPR84CA1CA2 | |
| SCHEMBL15826494 | 0.80 | GPR84 (0.64) | HTR2AGAAGPR84CA1CA2 | |
| SCHEMBL6588553 | 0.77 | GPR84 (0.50) | HTR2CHTR2AGAAALDH1A1GPR84 | |
| Phosphoric Acid SCHEMBL6340345 | 0.76 | GPR84 (0.50) | HTR2CHTR2AHTR2BGAAKDM4E | |
| SCHEMBL28417664 | 0.76 | GPR84 (0.42) | HTR2CHTR2AHTR2BALDH1A1KMT2A | |
| SCHEMBL1224297 | 0.75 | GPR84 (0.58) | HTR2CHTR2AHTR2BGAAGPR84 | |
| SCHEMBL788532 | 0.75 | HTR2C (0.51) | HTR2CHTR2AHTR2BGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | claimed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | disclosed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |