Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912340 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL7644528 | 0.78 | MAPT (0.40) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL27780340 | 0.78 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL29401517 | 0.78 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL7646920 | 0.78 | GPR35 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL29701589 | 0.78 | GPR35 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL16147716 | 0.78 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL1967927 | 0.78 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL27708037 | 0.78 | MAPT (0.43) | ALDH1A1MAPTLMNASMN1; SMN2ABCG2 | |
| SCHEMBL10537071 | 0.77 | NPC1 (0.42) | ALDH1A1MAPTLMNAMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797580-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | Pfleiderer, Wolfgang (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018634-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 1996-06-20 | — | — | WO | disclosed |