Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDM6A | O15550 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502422 | 0.78 | KDM4E (0.41) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL3256806 | 0.76 | HTR2C (0.40) | ASH1L | |
| SCHEMBL5501732 | 0.75 | HSD11B1 (0.39) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL31705935 | 0.75 | RHEB (0.42) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL5354038 | 0.75 | KDM4E (0.38) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL18876199 | 0.75 | HSD11B1 (0.41) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL18876105 | 0.75 | RHEB (0.42) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL22025573 | 0.75 | KDM4E (0.38) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL21603427 | 0.75 | DHFR (0.45) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 | |
| SCHEMBL5361046 | 0.73 | PTPN1 (0.40) | KDM4EHSD11B1ALDH1A1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | claimed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | claimed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | disclosed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |