Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443442 | 0.76 | CCR2 (0.56) | CCR2FEN1L3MBTL1ADRA1DERCC5 | |
| SCHEMBL8438818 | 0.76 | L3MBTL1 (0.49) | CCR2FEN1L3MBTL1ADRA1DFAAH | |
| SCHEMBL25395450 | 0.75 | CCR2 (0.55) | CCR2FEN1L3MBTL1ADRA1DFAAH | |
| SCHEMBL10543693 | 0.73 | CCR2 (0.56) | CCR2FEN1ADRA1DERCC5FAAH | |
| SCHEMBL7359634 | 0.72 | L3MBTL1 (0.57) | CCR2L3MBTL1ADRA1DBRD4FAAH | |
| SCHEMBL6433076 | 0.71 | CCR2 (0.77) | CCR2FEN1CFTR | |
| SCHEMBL7359317 | 0.70 | KLKB1 (0.51) | CCR2FEN1L3MBTL1BRD4POLB | |
| SCHEMBL8126612 | 0.70 | FEN1 (0.52) | CCR2FEN1L3MBTL1ERCC5FAAH | |
| SCHEMBL6432935 | 0.70 | CCR2 (0.64) | CCR2FEN1 | |
| SCHEMBL8441612 | 0.70 | CCR2 (0.49) | CCR2FEN1L3MBTL1ERCC5BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612363-A | FACTOR XA INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1997-03-18 | — | — | US | disclosed |