Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57306 | 0.97 | — | — | |
| SCHEMBL21954031 | 0.97 | HRH3 (0.38) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| SCHEMBL8648295 | 0.97 | — | — | |
| SCHEMBL18085476 | 0.94 | SMN1; SMN2 (0.40) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| Hydrochloric Acid SCHEMBL2139284 | 0.94 | PRKCG (0.40) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| SCHEMBL24590305 | 0.94 | SMN1; SMN2 (0.40) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| SCHEMBL5962431 | 0.94 | SMN1; SMN2 (0.40) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| SCHEMBL14261286 | 0.94 | SMN1; SMN2 (0.40) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| SCHEMBL441543 | 0.87 | PRKCG (0.37) | HRH3PRKCGPRKCBPRKCAKCNA5 | |
| SCHEMBL10237822 | 0.85 | ALDH1A1 (0.38) | HRH3PRKCGPRKCBPRKCAKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2759016-A1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | Bromine Compounds Ltd. (IL) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013042110-A1 | ADDITIVES FOR HYDROGEN/ BROMINE CELLS | BROMINE COMPOUNDS LTD. (IL) | 2013-03-28 | — | — | WO | disclosed |
| US-5702842-A | Process for charging and discharging zinc/bromine batteries | ELIN ENERGIEANWENDUNG GESELLSCHAFT M.B.H. (AT) | 1997-12-30 | — | — | US | disclosed |