Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.54 |
| ▸ | HTR2A | P28223 | 14/20 | 0.54 |
| ▸ | HTR2C | P28335 | 14/20 | 0.54 |
| ▸ | HTR2B | P41595 | 14/20 | 0.54 |
| ▸ | DRD2 | P14416 | 13/20 | 0.51 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841626 | 0.75 | SIGMAR1 (0.68) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7587346 | 0.72 | SIGMAR1 (0.73) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL14637745 | 0.72 | SIGMAR1 (0.70) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6836356 | 0.72 | SIGMAR1 (1.00) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6841585 | 0.71 | SIGMAR1 (0.63) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL9451756 | 0.71 | SIGMAR1 (0.71) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL30486456 | 0.71 | SIGMAR1 (0.43) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL14638454 | 0.69 | SIGMAR1 (0.59) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL16407590 | 0.69 | SIGMAR1 (0.66) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6841309 | 0.68 | SIGMAR1 (1.00) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633247-A | ANTIARRTHYMIA AGENT | MERCK & CO., INC. (US) | 1997-05-27 | — | — | US | disclosed |