Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805646 | 0.85 | GAA (0.62) | MMP8GAAPIN1MEN1KMT2A | |
| SCHEMBL23027214 | 0.85 | GAA (0.62) | MMP8GAAPIN1MEN1KMT2A | |
| SCHEMBL260296 | 0.85 | GAA (0.62) | MMP8GAAPIN1MEN1KMT2A | |
| SCHEMBL5972492 | 0.85 | MMP8 (0.56) | MMP8GAAPIN1MEN1NPC1 | |
| SCHEMBL5811954 | 0.84 | MMP8 (0.54) | MMP8GAAPIN1MEN1NPC1 | |
| Hydrogen Sulfide SCHEMBL28874620 | 0.84 | GAA (0.60) | MMP8GAAPIN1MEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL27877648 | 0.84 | GAA (0.60) | MMP8GAAPIN1MEN1KMT2A | |
| SCHEMBL10635430 | 0.84 | MMP8 (0.54) | MMP8GAAPIN1MEN1NPC1 | |
| SCHEMBL7684411 | 0.83 | SMN1; SMN2 (0.55) | MMP8GAAPIN1MEN1NPC1 | |
| SCHEMBL8912908 | 0.82 | MMP8 (0.53) | MMP8GAAPIN1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |