Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721120 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL7128339 | 0.89 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL12169382 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL30579937 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL10037177 | 0.88 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL12188931 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL31086809 | 0.85 | MMP9 (0.67) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL32691722 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AHSD11B1LMNA | |
| SCHEMBL30702743 | 0.83 | GAA (0.63) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL31265161 | 0.83 | GAA (0.63) | ALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591854-A | CATALYTIC CONDENSATION OF DIENES AND VINYLDIAZOMETHANEESTERS | WAKE FOREST UNIVERSITY (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996011928-A1 | ENANTIOSELECTIVE SYNTHESIS OF SEVEN-MEMBERED CARBOCYCLES AND TROPANES | WAKE FOREST UNIVERSITY (US) | 1996-04-25 | — | — | WO | disclosed |