SCHEMBL8913075

SCHEMBL8913075

Cc1ccc(O)c(-c2ccccc2Cc2c[nH]nn2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.40
HPGD P15428 7/20 0.40
MAPT P10636 6/20 0.40
MEN1 O00255 6/20 0.40
ALOX15 P16050 3/20 0.40
USP2 O75604 2/20 0.40
NPSR1 Q6W5P4 5/20 0.38
CASP3 P42574 3/20 0.38
SENP8 Q96LD8 3/20 0.38
SENP7 Q9BQF6 3/20 0.38
SENP6 Q9GZR1 3/20 0.38
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 5/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 1/20 0.37
HSD17B10 Q99714 1/20 0.37
IDO1 P14902 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931499 0.85 HSPA5 (0.37) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL304360 0.78 HPGD (0.48) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL8911784 0.76 IDO1 (0.34) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL2854051 0.76 HSPA5 (0.52) IDO1
SCHEMBL2825597 0.73 DPP4 (0.43) KMT2A
SCHEMBL28789387 0.71 HPGD (0.48) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL15796454 0.71 GAA (0.41) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL29167681 0.68 NPSR1 (0.45) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL31351790 0.68 TRPA1 (0.52) KMT2AHPGDMAPTMEN1ALOX15
SCHEMBL3484810 0.68 TRPA1 (0.52) KMT2AHPGDMAPTMEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421259-B2 Perforated polyolefin films ACHILLES USA, INC. (US) 2019-09-24 US disclosed
US-20180257352-A1 PERFORATED POLYOLEFIN FILMS ACHILLES USA, INC. 2018-09-13 US disclosed
WO-2017031409-A1 PERFORATED POLYOLEFIN FILMS ACHILLES USA, INC. (US) 2017-02-23 WO disclosed
US-20140356566-A1 MULTI-LAYER POLYOLEFIN FILMS AND USES THEREOF ACHILLES USA, INC. (US) 2014-12-04 US disclosed
US-5698621-A BLEND CONTAINING STABILIZER AND PLASTICIZER ACHILLES USA, INC. (US) 1997-12-16 US disclosed