SCHEMBL8911784

SCHEMBL8911784

Cc1ccc(O)c(-c2ccc(Cl)c(Cl)c2Cc2c[nH]nn2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.34
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
MAPT P10636 8/20 0.32
KDM4E B2RXH2 1/20 0.32
HPGD P15428 6/20 0.32
ALOX15 P16050 3/20 0.32
NFKB1 P19838 2/20 0.32
RAB9A P51151 2/20 0.32
NFKB2 Q00653 2/20 0.32
RELA Q04206 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
USP2 O75604 2/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
JAK2 O60674 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8913075 0.76 KMT2A (0.40) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL28789387 0.68 HPGD (0.48) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL304360 0.66 HPGD (0.48) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL30046067 0.63 TRPA1 (0.65) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL278520 0.63 TRPA1 (0.65) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL29763149 0.63 TRPA1 (0.65) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL3388191 0.62 NPC1 (0.37) MEN1KMT2AMAPTHPGDALOX15
SCHEMBL30545218 0.61 IDO1 (0.39) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL15796454 0.60 GAA (0.41) IDO1MEN1KMT2AMAPTKDM4E
SCHEMBL20194472 0.60 BACE1 (0.45) IDO1MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421259-B2 Perforated polyolefin films ACHILLES USA, INC. (US) 2019-09-24 US disclosed
US-20180257352-A1 PERFORATED POLYOLEFIN FILMS ACHILLES USA, INC. 2018-09-13 US disclosed
WO-2017031409-A1 PERFORATED POLYOLEFIN FILMS ACHILLES USA, INC. (US) 2017-02-23 WO disclosed
US-20140356566-A1 MULTI-LAYER POLYOLEFIN FILMS AND USES THEREOF ACHILLES USA, INC. (US) 2014-12-04 US disclosed
US-5698621-A BLEND CONTAINING STABILIZER AND PLASTICIZER ACHILLES USA, INC. (US) 1997-12-16 US disclosed