Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NT5E | P21589 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445342 | 1.00 | AHCY (0.67) | AHCYLMNANT5EHIF1AADORA3 | |
| SCHEMBL8913103 | 1.00 | AHCY (0.67) | AHCYLMNANT5EHIF1AADORA3 | |
| SCHEMBL8912036 | 0.89 | AHCY (0.62) | AHCYLMNANT5EHIF1AADORA3 | |
| SCHEMBL9445334 | 0.89 | AHCY (0.62) | AHCYLMNANT5EHIF1AADORA3 | |
| SCHEMBL8912042 | 0.89 | AHCY (0.62) | AHCYLMNANT5EHIF1AADORA3 | |
| SCHEMBL9445425 | 0.87 | PDE4D (0.61) | AHCYLMNAADORA3ADORA2AADORA1 | |
| SCHEMBL8913282 | 0.87 | PDE4D (0.61) | AHCYLMNAADORA3ADORA2AADORA1 | |
| SCHEMBL8913285 | 0.87 | PDE4D (0.61) | AHCYLMNAADORA3ADORA2AADORA1 | |
| SCHEMBL8913539 | 0.83 | AHCY (0.63) | AHCYADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL8913548 | 0.83 | AHCY (0.63) | AHCYADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | claimed |
| EP-0491793-A4 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | — | 1993-03-03 | — | — | EP | claimed |
| EP-0491793-A1 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1992-07-01 | — | — | EP | claimed |
| WO-1991004033-A1 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1991-04-04 | — | — | WO | claimed |
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | disclosed |
| EP-0491793-A4 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | — | 1993-03-03 | — | — | EP | disclosed |
| EP-0491793-A1 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1991004033-A1 | 2'-DEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AND ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1991-04-04 | — | — | WO | disclosed |