Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.61 |
| ▸ | PNP | P00491 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | AHCY | P23526 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445425 | 1.00 | PDE4D (0.61) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL8913285 | 1.00 | PDE4D (0.61) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL8912042 | 0.88 | AHCY (0.62) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL9445334 | 0.88 | AHCY (0.62) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL8912036 | 0.88 | AHCY (0.62) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL9445342 | 0.87 | AHCY (0.67) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL8913103 | 0.87 | AHCY (0.67) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL8913115 | 0.87 | AHCY (0.67) | PDE4DPDE3APNPLMNATP53 | |
| SCHEMBL5066601 | 0.82 | AHCY (0.63) | SMN1; SMN2ADORA3ADORA2AADORA1AHCY | |
| SCHEMBL5066600 | 0.82 | AHCY (0.63) | SMN1; SMN2ADORA3ADORA2AADORA1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | claimed |
| US-5591722-A | ANTICANCER AGENTS | SOUTHERN RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | disclosed |