Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | OGG1 | O15527 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15697530 | 0.87 | LMNA (0.61) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL1745439 | 0.86 | LMNA (0.60) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL5034495 | 0.83 | SENP5 (0.59) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL9025214 | 0.83 | LMNA (0.69) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL31078467 | 0.81 | LMNA (0.55) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL4651635 | 0.81 | LMNA (0.55) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL1744992 | 0.80 | LMNA (0.57) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL15698894 | 0.79 | LMNA (0.63) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL11377056 | 0.79 | LMNA (0.58) | LMNAMAPK1MAPTALDH1A1KMT2A | |
| SCHEMBL15697507 | 0.78 | LMNA (0.61) | LMNAMAPK1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612330-A | HERPES VIRUS | WARNER-LAMBERT COMPANY (US) | 1997-03-18 | — | — | US | disclosed |