Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL30028929 | 0.88 | CHRM2 (0.39) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL25079048 | 0.87 | CHRM2 (0.59) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL4521492 | 0.86 | CHRM2 (0.53) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL5351903 | 0.86 | CHRM2 (0.53) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL6618554 | 0.83 | LMNA (0.50) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL6618555 | 0.83 | LMNA (0.50) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL636999 | 0.82 | CHRM2 (0.58) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL22777402 | 0.80 | CHRM2 (0.57) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL15421001 | 0.80 | CHRM2 (0.57) | CHRM2CHRM4CHRM5ALDH1A1KMT2A | |
| SCHEMBL10120550 | 0.80 | CHRM2 (0.57) | CHRM2CHRM4CHRM5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022175402-A1 | QUINUCLIDINE-3-ONE DERIVATIVES | APREA THERAPEUTICS AB (SE) | 2022-08-25 | — | — | WO | disclosed |
| WO-2010075273-A1 | BICYCLIC HETEROCYCLE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-07-01 | — | — | WO | disclosed |
| US-5641786-A | Quinuclidine derivatives | LOWE III JOHN ADAMS (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0540526-B1 | QUINUCLIDINE DERIVATIVES | PFIZER (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0540526-A1 | QUINUCLIDINE DERIVATIVES. | PFIZER (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001688-A1 | QUINUCLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-02-06 | — | — | WO | disclosed |