Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GOT1 | P17174 | 1/20 | 0.37 |
| ▸ | CFB | P00751 | 4/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415599 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL24872829 | 0.84 | OPRK1 (0.39) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL29916391 | 0.84 | HPGD (0.45) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL806532 | 0.81 | CFB (0.40) | KDM4EALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL6870400 | 0.74 | AXL (0.40) | CYP1A2GOT1CFBKMT2AAXL | |
| SCHEMBL30219091 | 0.74 | AHR (0.42) | ALDH1A1PARP1GOT1CFBKMT2A | |
| SCHEMBL24810964 | 0.74 | CFB (0.36) | KDM4EALDH1A1LMNACYP3A4CYP2C9 | |
| SCHEMBL6870752 | 0.74 | TNF (0.39) | PARP1GOT1CFBAXLPRKCI | |
| SCHEMBL265821 | 0.74 | AHR (0.42) | ALDH1A1PARP1GOT1CFBKMT2A | |
| SCHEMBL6192602 | 0.74 | TDP1 (0.38) | KDM4EALDH1A1CYP3A4PARP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | claimed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | claimed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | claimed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | claimed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | claimed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| US-20250100967-A1 | HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | Enveric Biosciences Canada Inc. (CA) | 2025-03-27 | — | — | US | disclosed |
| US-12187679-B2 | Hydroxylated psilocybin derivatives and methods of using | Enveric Biosciences Canada Inc. (CA) | 2025-01-07 | — | — | US | disclosed |
| CN-117897376-A | Heterocyclic compounds and process for preparing same | 光明智慧生物科学公司 | 2024-04-16 | — | — | CN | disclosed |
| US-20230043896-A1 | HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | MAGICMED INDUSTRIES INC. (CA) | 2023-02-09 | — | — | US | disclosed |
| WO-2022047580-A1 | HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | MAGICMED INDUSTRIES INC. (CA) | 2022-03-10 | — | — | WO | disclosed |
| EP-2464424-B1 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND AN INDOLE COUPLER | OREAL (FR) | 2019-09-25 | — | — | EP | disclosed |
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |
| EP-0428441-B1 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | OREAL (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | disclosed |
| EP-0446131-A1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | L'OREAL (FR) | 1991-09-11 | — | — | EP | disclosed |
| CN-1051668-A | Contain the dyeing composition for keratinous fibres of oxidation colorant parent and 4-hydroxy indoxyl derivative colour former and use the staining that said composition is carried out | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0428441-A2 | Keratinic fibre dyeing compostions containing oxydation dye precursors and derivatives of 4-hydroxyindole as couplers, and dyeing process using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250100967-A1 | HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | HTR1B, HTR2B, CYP8B1 | KDM4E 2536/4885ALDH1A1 799/4885LMNA 4415/4885 |
| US-20230043896-A1 | HYDROXYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | HTR1B, HTR2B, CYP8B1 | KDM4E 2536/4885ALDH1A1 799/4885LMNA 4415/4885 |
| US-12187679-B2 | Hydroxylated psilocybin derivatives and methods of using | HTR1B, HTR2B, CYP8B1 | KDM4E 2536/4885ALDH1A1 799/4885LMNA 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.