Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415599 | 0.84 | KDM4E (0.38) | OPRK1KMT2AASH1LSLC6A2HTT | |
| SCHEMBL8913181 | 0.84 | KDM4E (0.38) | OPRK1KMT2AASH1LSLC6A2HTT | |
| SCHEMBL806532 | 0.83 | CFB (0.40) | KMT2ACYP1A2KDM4EALDH1A1LMNA | |
| Ethoxycarbonyl Group SCHEMBL27352012 | 0.80 | NUDT1 (0.33) | KMT2AASH1LCYP1A2ALDH1A1CYP3A4 | |
| SCHEMBL29916391 | 0.80 | HPGD (0.45) | KMT2AASH1LCYP1A2KDM4EALDH1A1 | |
| SCHEMBL2768928 | 0.76 | DRD4 (0.39) | KMT2ACYP1A2KDM4EALDH1A1LMNA | |
| SCHEMBL1465882 | 0.76 | AHR (0.42) | KMT2ACYP1A2AXLPRKCICCR8 | |
| SCHEMBL2983820 | 0.76 | ALDH1A1 (0.38) | KMT2ACYP1A2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL806287 | 0.76 | TNF (0.39) | KMT2ACYP1A2PARP1ACHEAXL | |
| SCHEMBL15280126 | 0.76 | CYP1A2 (0.33) | KMT2ACYP1A2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280177-A1 | SMALL MOLECULE COMPOUND TARGETING BCL9/β-CATENIN INTERACTION | 南通聚太生物科技有限公司 | 2023-01-12 | — | — | WO | disclosed |