Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.66 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.66 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402300 | 0.82 | SRD5A2 (0.87) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL6539309 | 0.81 | MAOB (0.61) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL4059143 | 0.80 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL6830467 | 0.80 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL3232949 | 0.80 | SRD5A2 (0.90) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL228477 | 0.80 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL10386413 | 0.79 | MRGPRX4 (0.56) | SMN1; SMN2RAB9ANPC1LMNAHDAC6 | |
| SCHEMBL10386412 | 0.79 | MRGPRX4 (0.56) | SMN1; SMN2RAB9ANPC1LMNAHDAC6 | |
| SCHEMBL11398209 | 0.79 | NR4A2 (0.72) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| Hydrochloric Acid SCHEMBL8544438 | 0.78 | NR4A2 (0.96) | NR4A2NR4A1NR4A3MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |