SCHEMBL8913311

SCHEMBL8913311

O=C(Cl)C(=O)C(=O)C(=O)C(=O)C(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 12/20 0.56
CES1 P23141 12/20 0.56
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA5A P35218 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA13 Q8N1Q1 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CA5B Q9Y2D0 1/20 0.46
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
TRPA1 O75762 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8912371 0.98 CES1 (0.59) CES2CES1CA12CA1CA2
SCHEMBL3686005 0.91 CES1 (0.62) CES2CES1CA12CA1CA2
SCHEMBL15658164 0.88 CES2 (0.72) CES2CES1CA12CA1CA2
SCHEMBL15656687 0.88 CES2 (0.72) CES2CES1CA12CA1CA2
SCHEMBL27737798 0.85 CES2 (0.77) CES2CES1CA12CA1CA2
SCHEMBL263843 0.80 CES1 (0.68) CES2CES1CA12CA1CA2
SCHEMBL6520575 0.80 CES1 (0.68) CES2CES1CA12CA1CA2
SCHEMBL61363 0.80 CES2 (0.77) CES2CES1CA12CA1CA2
Water SCHEMBL10351087 0.78 CES1 (0.65) CES2CES1CA12CA1CA2
Benzil SCHEMBL35210470 0.78 CES2 (0.82) CES2CES1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5674398-A THIN FILM OF CROSSLINKED POLYAMIDE OBTAINED BY INTERFACIAL POLYMERIZATION AND MICROPOROUS SUBSTRATE NITTO DENKO CORPORATION (JP) 1997-10-07 US disclosed