SCHEMBL891351

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7363268	0.81	ALDH1A1 (0.66)	ALDH1A1GLATSHRTP53HTT
	SCHEMBL9297945	0.81	ADRA2C (0.49)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL7504930	0.80	TSHR (0.48)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL1416009	0.80	ALDH1A1 (0.48)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL28961966	0.79	GAA (0.45)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL27528022	0.79	HDAC3 (0.54)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL9471518	0.79	NPC1 (0.69)	ALDH1A1GLATSHRHTTSMN1; SMN2
	SCHEMBL9157921	0.78	ADRA2C (0.46)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL7742452	0.78	ALDH1A1 (0.43)	ALDH1A1GLATSHRADRA2CTP53
	SCHEMBL27348465	0.77	GAA (0.50)	ALDH1A1GLATSHRADRA2CTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.