Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 6/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344885 | 0.85 | AHR (0.46) | IDO1AKR1B1PDE7ATGM2CES1 | |
| SCHEMBL5873792 | 0.78 | LMNA (0.50) | MGAMGAASIMGAM2AKR1B1 | |
| SCHEMBL2265588 | 0.78 | IDO1 (0.53) | IDO1MGAMHTR1AGAASI | |
| SCHEMBL1722012 | 0.77 | PGR (0.69) | IDO1AKR1B1PDE7AMEN1KMT2A | |
| SCHEMBL29224118 | 0.77 | CYP1A2 (0.56) | HTR7AKR1B1KMT2APGRAKR1A1 | |
| SCHEMBL30463281 | 0.77 | CYP1A2 (0.56) | HTR7AKR1B1KMT2APGRAKR1A1 | |
| SCHEMBL7471467 | 0.76 | MAPT (0.50) | IDO1MGAMHTR1AGAASI | |
| SCHEMBL29860221 | 0.76 | PGR (0.69) | IDO1MGAMHTR1AGAASI | |
| SCHEMBL26666506 | 0.76 | PGR (0.69) | IDO1MGAMHTR1AGAASI | |
| SCHEMBL5345525 | 0.75 | AKR1C3 (0.47) | IDO1MGAMHTR1AGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0570817-B1 | Process for the preparation of 5-chloroxindole | LONZA AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| US-5395963-A | Process for chloronitroacetic acid esters | LONZA LTD. (CH) | 1995-03-07 | — | — | US | disclosed |
| US-5284960-A | Process for the production of 5-chloroxindole | LONZA LTD. (CH) | 1994-02-08 | — | — | US | disclosed |
| EP-0570817-A1 | Process for the preparation of 5-chloroxindole | LONZA A.G. (CH) | 1993-11-24 | — | — | EP | disclosed |
| US-4885370-A | Synthetic method for indol-2(3H)-ones | PFIZER INC. (US) | 1989-12-05 | — | — | US | disclosed |
| US-4761485-A | Synthetic method for indol-2(3H)-ones | PFIZER INC. (US) | 1988-08-02 | — | — | US | disclosed |