Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazole SCHEMBL5064075 | 0.84 | HCAR2 (0.31) | — | |
| Pyrazole SCHEMBL20495491 | 0.84 | — | — | |
| Oxalic Acid SCHEMBL27899728 | 0.81 | HCAR2 (0.30) | — | |
| Oxalic Acid SCHEMBL27705066 | 0.81 | HCAR2 (0.30) | — | |
| Pyrazole SCHEMBL1768971 | 0.79 | — | — | |
| Pyrazole SCHEMBL440249 | 0.79 | — | — | |
| Pyrazole SCHEMBL28097841 | 0.78 | — | — | |
| Pyrazole SCHEMBL27452811 | 0.78 | — | — | |
| Benzene SCHEMBL27522565 | 0.78 | — | — | |
| Benzene SCHEMBL27971048 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108709879-A | Surface-enhanced Raman scattering activity film based on the high-elastic polymer of dielectric and method | 浙江大学 | 2018-10-26 | — | — | CN | claimed |
| CN-115244043-B | Benzimidazolone cinnamamide derivatives as TRPV1 antagonists and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-117304172-A | Compounds, pharmaceutical compositions, methods of making and methods of treating diseases | 密执安大学评议会 | 2023-12-29 | — | — | CN | disclosed |
| CN-111315383-B | Small molecule inhibitors sharing epitope-calreticulin interactions and methods of use | 密执安大学评议会 | 2023-09-29 | — | — | CN | disclosed |
| US-11613528-B2 | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-03-28 | — | — | US | disclosed |
| CN-115244043-A | Benzimidazolonyl cinnamamide derivative as TRPV1 antagonist and pharmaceutical composition for treating or preventing pain containing the same as active ingredient | 杰迈肯有限公司 | 2022-10-25 | — | — | CN | disclosed |
| EP-3706744-B1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | UNIV MICHIGAN REGENTS (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-113788929-B | Self-repairing and recyclable bio-based polyurethane material and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2022-06-10 | — | — | CN | disclosed |
| US-20220106292-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2022-04-07 | — | — | US | disclosed |
| US-11168071-B2 | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200299268-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2020-09-24 | — | — | US | disclosed |
| EP-3706744-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | The Regents of The University of Michigan (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10723718-B2 | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2020-07-28 | — | — | US | disclosed |
| CN-111315383-A | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | 密执安大学评议会 | 2020-06-19 | — | — | CN | disclosed |
| WO-2019188369-A1 | OIL-REPELLENT AND WATER-REPELLENT AGENT COMPOSITION, ARTICLE, AND METHOD FOR PRODUCING ARTICLE | ＡＧＣ株式会社 | 2019-10-03 | — | — | WO | disclosed |
| WO-2019172021-A1 | METHOD FOR PRODUCING WATER-AND-OIL REPELLENT COMPOSITION, AND METHOD FOR PRODUCING WATER-AND-OIL REPELLENT ARTICLE | ＡＧＣ株式会社 | 2019-09-12 | — | — | WO | disclosed |
| US-20190135783-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-05-09 | — | — | US | disclosed |
| CN-108709879-A | Surface-enhanced Raman scattering activity film based on the high-elastic polymer of dielectric and method | 浙江大学 | 2018-10-26 | — | — | CN | disclosed |
| US-5606073-A | INTERMEDIATES FOR ADENOSINE ANTAGONISTS | EISAI CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723718-B2 | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | CALR, PTPRC, PTPRJ | LMNA 4048/4885AKT1 2241/4885ALOX15 3328/4885 |
| US-11613528-B2 | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | CALR, PTPRC, PTPRJ | LMNA 4026/4885AKT1 2270/4885ALOX15 3353/4885 |
| US-11168071-B2 | Small molecule inhibitors of shared epitope-calreticulin interactions and methods of use | CALR, PTPRC, PTPRJ | LMNA 4026/4885AKT1 2270/4885ALOX15 3353/4885 |
| US-20220106292-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | CALR, PTPRC, PTPRJ | LMNA 4026/4885AKT1 2270/4885ALOX15 3353/4885 |
| US-20190135783-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | CALR, PTPRC, PTPRJ | LMNA 4026/4885AKT1 2270/4885ALOX15 3353/4885 |
| US-20200299268-A1 | SMALL MOLECULE INHIBITORS OF SHARED EPITOPE-CALRETICULIN INTERACTIONS AND METHODS OF USE | CALR, PTPRC, PTPRJ | LMNA 4026/4885AKT1 2270/4885ALOX15 3353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.