Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914255 | 0.78 | TRPM5 (0.34) | TRPM5CHRNA7 | |
| SCHEMBL1694510 | 0.77 | CYP1A2 (0.40) | TRPM5CHRNA7MAPK1 | |
| SCHEMBL8179979 | 0.73 | CYP1A2 (0.44) | TRPM5 | |
| SCHEMBL6184266 | 0.73 | TRPM5 (0.38) | TRPM5CHRNA7 | |
| SCHEMBL1999837 | 0.72 | TRPM5 (0.44) | TRPM5CHRNA7 | |
| SCHEMBL22955088 | 0.70 | TRPM5 (0.39) | TRPM5BRD4 | |
| SCHEMBL9343342 | 0.70 | CNR1 (0.39) | TRPM5 | |
| SCHEMBL4717777 | 0.70 | MAPT (0.47) | MAPK1 | |
| SCHEMBL16924219 | 0.70 | CA1 (0.44) | TRPM5CHRNA7BRD4 | |
| SCHEMBL13500589 | 0.70 | NPC1 (0.49) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633364-A | N4 -substituted 2'-deoxycytidine compounds, oligonucleotides including N4 -labeled 2'-deoxycytidines, and a process for making oligonucleotides with N-modified 2'-deoxycytidines | AMOCO CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5405950-A | N4 -substituted cytidines and process for incorporation into an oligonucleotides | AMOCO CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |