SCHEMBL8914255

SCHEMBL8914255

O=[C]NOCc1ccc2oncc2c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPM5 Q9NZQ8 1/20 0.34
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRNA7 P36544 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068060 0.81 LMNA (0.33) TRPM5LMNATP53CHRNA7
SCHEMBL8913585 0.78 TRPM5 (0.39) TRPM5CHRNA7
SCHEMBL20079989 0.75 LMNA (0.49) TRPM5LMNATP53
SCHEMBL9979773 0.72 CYP3A4 (0.49) TRPM5LMNATP53CHRNA7
SCHEMBL115421 0.72 LMNA (0.40) TRPM5LMNATP53CHRNA7
SCHEMBL3290937 0.72 ALDH1A1 (0.44) TRPM5LMNATP53CHRNA7
SCHEMBL8179979 0.70 CYP1A2 (0.44) TRPM5LMNATP53
SCHEMBL13500589 0.70 NPC1 (0.49) LMNATP53
SCHEMBL1999837 0.69 TRPM5 (0.44) TRPM5LMNATP53CHRNA7
SCHEMBL1694510 0.68 CYP1A2 (0.40) TRPM5LMNATP53CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633364-A N4 -substituted 2'-deoxycytidine compounds, oligonucleotides including N4 -labeled 2'-deoxycytidines, and a process for making oligonucleotides with N-modified 2'-deoxycytidines AMOCO CORPORATION (US) 1997-05-27 US claimed