Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | UGCG | Q16739 | 2/20 | 0.46 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.46 |
| ▸ | OSBP | P22059 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913660 | 0.94 | POLA1 (0.50) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8916630 | 0.92 | POLA1 (0.47) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8915436 | 0.89 | PLA2G2A (0.49) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8915187 | 0.86 | POLA1 (0.42) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8914377 | 0.85 | POLA1 (0.49) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8917330 | 0.85 | POLA1 (0.43) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8914667 | 0.83 | PLA2G2A (0.50) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8915147 | 0.81 | PLA2G2A (0.39) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL8174993 | 0.80 | CYP46A1 (0.50) | POLA1CYP46A1GBA1UGCGGBA2 | |
| SCHEMBL6419070 | 0.78 | POLA1 (0.79) | POLA1CYP46A1GBA1UGCGGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643889-A | Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF PENNSYLVANIA (US) | 1997-07-01 | — | — | US | disclosed |