SCHEMBL8915147

CC(C)CCC[C@@H](C)[C@H]1CCC2C3CC=C4CCC(C(=O)CCC(=O)O[C@@H]5C[C@@H](COP(=O)(O)O[C@@H]6C[C@@H](COP(=O)(O)O[C@@H]7C[C@@H](CO)O[C@H]7n7cnc8c(N)ncnc87)O[C@H]6n6cnc7c(N)ncnc76)O[C@H]5n5cnc6c(N)ncnc65)C[C@]4(C)C3CC[C@@]21C

nearest known ligand 0.41

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	PLA2G2A	P14555	1/20	0.39

▸	POLA1	P09884	1/20	0.38

▸	USP2	O75604	2/20	0.37

▸	CYP46A1	Q9Y6A2	2/20	0.36

▸	LMNA	P02545	1/20	0.36

▸	ABCB1	P08183	1/20	0.36

▸	OSBP	P22059	1/20	0.36

▸	RORC	P51449	1/20	0.36

▸	OSBP2	Q969R2	1/20	0.36

▸	SRD5A1	P18405	3/20	0.36

▸	NPC1L1	Q9UHC9	2/20	0.34

▸	GBA1	P04062	2/20	0.34

▸	UGCG	Q16739	2/20	0.34

▸	GBA2	Q9HCG7	2/20	0.34

▸	FNTA	P49354	1/20	0.33

▸	FNTB	P49356	1/20	0.33

▸	NR1H3	Q13133	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8915436	0.91	PLA2G2A (0.49)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8915187	0.88	POLA1 (0.42)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8913660	0.85	POLA1 (0.50)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8914667	0.84	PLA2G2A (0.50)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8916630	0.82	POLA1 (0.47)	POLA1USP2CYP46A1LMNAABCB1
SCHEMBL8913664	0.81	POLA1 (0.51)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8914377	0.76	POLA1 (0.49)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8174993	0.73	CYP46A1 (0.50)	PLA2G2APOLA1USP2CYP46A1LMNA
SCHEMBL8174627	0.71	OSBP (0.47)	POLA1USP2CYP46A1LMNAABCB1
SCHEMBL8917330	0.69	POLA1 (0.43)	PLA2G2APOLA1USP2CYP46A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5643889-A	Cholesterol conjugates of 2'5'-oligoadenylate derivatives and antiviral uses thereof	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF PENNSYLVANIA (US)	1997-07-01	—	—	US	claimed