SCHEMBL8913712

SCHEMBL8913712

OCCOc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 3/20 0.42
RECQL P46063 1/20 0.42
KDM4E B2RXH2 4/20 0.40
MAPK1 P28482 2/20 0.40
HPGD P15428 2/20 0.40
POLB P06746 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ACSS2 Q9NR19 1/20 0.38
GAA P10253 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
FGFR1 P11362 1/20 0.38
SRC P12931 1/20 0.38
PDE2A O00408 1/20 0.38
PDE10A Q9Y233 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6474039 0.91 NPC1 (0.45) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL8854056 0.90 NPC1 (0.44) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL11135110 0.89 NPC1 (0.54) NPC1RAB9ALMNAALDH1A1RECQL
SCHEMBL21145629 0.87 NPC1 (0.46) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL7141357 0.87 GPBAR1 (0.46) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL29463600 0.87 GPBAR1 (0.46) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL29510555 0.87 NPC1 (0.46) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL508086 0.86 NPC1 (0.41) NPC1RAB9ALMNAALDH1A1KDM4E
SCHEMBL8914751 0.85 KMT2A (0.37) NPC1RAB9AKDM4EHPGDCA1
SCHEMBL8997629 0.85 FFAR1 (0.43) NPC1RAB9ALMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7145246-A None JP disclosed
JP-7145247-A None JP disclosed
US-5674670-A HAVING GOOD STABILITY, HIGH EXTINCTION COEFFICIENT, LITTLE OR NO YELLOW COLORATION EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0750224-A2 2'-Hydroxyphenyl benzotriazole based UV absorbing polymers with particular substituents and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-12-27 EP disclosed
EP-0472819-B1 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ATOCHEM NORTH AMERICA ELF (US) 1996-08-21 EP disclosed
JP-H07145247-A MOLDED ARTICLE OF RESIN CONTAINING ULTRAVIOLET ABSORBER AND ITS PRODUCTION TAKIRON CO LTD 1995-06-06 JP disclosed
JP-H07145246-A MOLDED ARTICLE OF RESIN CONTAINING ULTRAVIOLET ABSORBER AND ITS PRODUCTION TAKIRON CO LTD 1995-06-06 JP disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
EP-0472819-A2 Polymeric peroxides derived from hydroxy-hydroperoxides and dihydroxy-dialkyl peroxides and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-03-04 EP disclosed
US-5039754-A Block copolymer;compatibilizing polymer blends and alloy ATOCHEM NORTH AMERICA, INC. (US) 1991-08-13 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed
WO-1989002906-A1 ULTRAVIOLET STABILIZED HALOGENATED POLYMER COMPOSITIONS EASTMAN KODAK COMPANY (US) 1989-04-06 WO disclosed
US-4271307-A Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1981-06-02 US disclosed
US-4076687-A Bichromophoric benzotriazole-benzoxazole ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-02-28 US disclosed