SCHEMBL8913744

SCHEMBL8913744

CCCc1ccc(OC(=O)c2ccc(CCC[Si]3(C)CCC(C)(C)O[Si]3(C)C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.39
THRB P10828 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
KMT2A Q03164 3/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
NPC1 O15118 3/20 0.36
PRSS1 P07477 2/20 0.36
ACR P10323 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
THRA P10827 1/20 0.34
LMNA P02545 2/20 0.33
F2 P00734 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9304072 0.93 PRSS1 (0.43) MAPTTHRBSMN1; SMN2KMT2ANPC1
SCHEMBL8913315 0.93 MAPT (0.41) MAPTTHRBSMN1; SMN2KMT2ANPC1
SCHEMBL8913271 0.92 SMN1; SMN2 (0.41) MAPTTHRBSMN1; SMN2KMT2ANPC1
SCHEMBL9303232 0.92 SMN1; SMN2 (0.41) MAPTTHRBSMN1; SMN2KMT2ANPC1
SCHEMBL8914086 0.89 F2 (0.38) MAPTSMN1; SMN2KMT2APRSS1ACR
SCHEMBL30354554 0.73 THRB (0.62) MAPTTHRBSMN1; SMN2KMT2APLA2G1B
SCHEMBL10633416 0.73 THRB (0.62) MAPTTHRBSMN1; SMN2KMT2APLA2G1B
SCHEMBL3612308 0.72 THRB (0.61) MAPTTHRBSMN1; SMN2KMT2APLA2G1B
SCHEMBL9842583 0.72 THRB (0.61) MAPTTHRBSMN1; SMN2KMT2APLA2G1B
SCHEMBL8377166 0.71 THRB (0.61) MAPTTHRBSMN1; SMN2KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35462-E Silylated benzoic acid derivatives CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) 1997-02-25 US disclosed
US-5277838-A Silylated benzoic acid derivatives CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1994-01-11 US disclosed
US-5106530-A Liquid crystals Consortium Fur Elektrochemische Ind. (DE) 1992-04-21 US disclosed