Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 3/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303232 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTTHRBTHRASPHK1 | |
| SCHEMBL8913315 | 0.99 | MAPT (0.41) | SMN1; SMN2MAPTTHRBTHRASPHK1 | |
| SCHEMBL8913744 | 0.92 | MAPT (0.39) | SMN1; SMN2MAPTTHRBTHRANFKB1 | |
| SCHEMBL9304072 | 0.91 | PRSS1 (0.43) | SMN1; SMN2MAPTTHRBNFKB1NFKB2 | |
| SCHEMBL8914086 | 0.85 | F2 (0.38) | SMN1; SMN2MAPTLMNAMEN1ALDH1A1 | |
| SCHEMBL9511143 | 0.76 | THRB (0.62) | SMN1; SMN2MAPTTHRBTHRANFKB1 | |
| SCHEMBL28235899 | 0.76 | THRB (0.62) | SMN1; SMN2MAPTTHRBTHRANFKB1 | |
| SCHEMBL8021213 | 0.76 | THRB (0.62) | SMN1; SMN2MAPTTHRBTHRANFKB1 | |
| SCHEMBL8375690 | 0.75 | THRB (0.64) | SMN1; SMN2MAPTTHRBTHRANFKB1 | |
| SCHEMBL9016853 | 0.75 | THRB (0.64) | SMN1; SMN2MAPTTHRBTHRANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35462-E | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKOCHEMISCHE IND. GMBH (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5277838-A | Silylated benzoic acid derivatives | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5106530-A | Liquid crystals | Consortium Fur Elektrochemische Ind. (DE) | 1992-04-21 | — | — | US | disclosed |