Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | BCHE | P06276 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL891377 | 0.99 | TDP1 (0.66) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9651298 | 0.98 | ALDH1A1 (0.65) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4261974 | 0.92 | ALDH1A1 (0.57) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9651229 | 0.91 | ALDH1A1 (0.56) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Sanguinarium SCHEMBL9651303 | 0.91 | BAD (0.70) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Chelerythrine SCHEMBL9651282 | 0.89 | ALDH1A1 (0.75) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL29353594 | 0.87 | ALDH1A1 (0.48) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4313884 | 0.85 | ALDH1A1 (0.76) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Chelerythrine SCHEMBL28629157 | 0.80 | ALDH1A1 (0.88) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| Sanguinarium SCHEMBL23524622 | 0.79 | BAD (1.00) | TDP1ALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906923-A1 | COMPOSITION AND METHOD FOR TREATING COVID-19 WITH ISOQUINOLINE ALKALOID | Phytobiotics Futterzusatzstoffe GmbH (DE) | 2021-11-10 | — | — | EP | claimed |
| US-20090222957-A1 | REGULATORY PROTEIN-REGULATORY REGION ASSOCIATIONS RELATED TO ALKALOID BIOSYNTHESIS | CERES INC. (US) | 2009-09-03 | — | — | US | claimed |
| EP-1866418-A2 | MODULATING PLANT ALKALOIDS | Ceres Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2007117693-A2 | REGULATORY PROTEIN-REGULATORY REGION ASSOCIATIONS RELATED TO ALKALOID BIOSYNTHESIS | CERES, INC. (US) | 2007-10-18 | — | — | WO | claimed |
| EP-1833839-A1 | QUATERNARY ALKALOID DERIVATIVES OF CHELIDONIUM MAJUS L | Nowicky, Wassyl (AT) | 2007-09-19 | — | — | EP | claimed |
| WO-2006113481-A1 | SECONDARY METABOLITE PRODUCTION VIA MANIPULATION OF GENOME METHYLATION | CERES INC. (US) | 2006-10-26 | — | — | WO | claimed |
| US-20060236421-A1 | Secondary metabolite production via manipulation of genome methylation | CERES, INC. | 2006-10-19 | — | — | US | claimed |
| WO-2006091676-A2 | MODULATING PLANT ALKALOIDS | CERES INC. (US) | 2006-08-31 | — | — | WO | claimed |
| WO-2006032380-A1 | QUATERNARY ALKALOID DERIVATIVES OF CHELIDONIUM MAJUS L | NOWICKY WASSILI (AT) | 2006-03-30 | — | — | WO | claimed |
| EP-0581926-B1 | ANIMAL FEEDSTUFF FOR GROWTH INCREASE | NEUFELD KLAUS (AT) | 1996-09-11 | — | — | EP | claimed |
| WO-1992000104-A1 | MUCOSAL DELIVERY SYSTEMS FOR TREATMENT OF PERIODONTAL DISEASE | ATRIX LABORATORIES, INC. (US) | 1992-01-09 | — | — | WO | claimed |
| US-5073368-A | Including a surfactant mixture of an amidobetaine and an ethylene oxide-propylene oxide copolymer | COLGATE-PALMOLIVE COMPANY (US) | 1991-12-17 | — | — | US | claimed |
| US-5066483-A | Benzophenanthridine alkaloids, buffer; stability; mouthwashes; plaque | VIPONT PHARMACEUTICAL, INC. (US) | 1991-11-19 | — | — | US | claimed |
| WO-1991007391-A1 | PURIFICATION OF BENZOPHENANTHRIDINE ALKALOIDS FROM ALKALOID EXTRACTS | ATRIX LABORATORIES, INC. (US) | 1991-05-30 | — | — | WO | claimed |
| US-5013553-A | Drug delivery devices | VIPONT PHARMACEUTICAL, INC. (US) | 1991-05-07 | — | — | US | claimed |
| WO-1991000728-A1 | BENZOPHENANTHRIDINE ALKALOIDS FOR TOPICAL ACNE TREATMENT | ATRIX LABORATORIES, INC. (US) | 1991-01-24 | — | — | WO | claimed |
| EP-0396232-A2 | Oral rinse compositions | VIPONT PHARMACEUTICAL, INC. (US) | 1990-11-07 | — | — | EP | claimed |
| EP-0297535-A2 | Drug delivery devices | VIPONT PHARMACEUTICAL, INC. (US) | 1989-01-04 | — | — | EP | claimed |
| US-4769452-A | Production of purity benzo-c-phenanthridine alkaloid salts | VIPONT LABORATORIES, INC. (US) | 1988-09-06 | — | — | US | claimed |
| US-4767861-A | Recovery of benzo-c-phenanthridine alkaloids | VIPONT LABORATORIES (US) | 1988-08-30 | — | — | US | claimed |