Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915100 | 1.00 | ADH1A (0.38) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6855095 | 0.88 | ADH1A (0.37) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL16941957 | 0.87 | ADH1A (0.30) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL9382078 | 0.85 | ADH1A (0.42) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL9382386 | 0.85 | ADH1A (0.42) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL9378522 | 0.85 | ADH1A (0.42) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7482550 | 0.82 | TLR9 (0.34) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL16941959 | 0.82 | TLR9 (0.34) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL8914778 | 0.82 | ADH1A (0.42) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL20801853 | 0.82 | ADH1A (0.43) | ADH1AKITFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099692-B9 | BIFUNCTIONAL CYTOTOXIC AGENTS | PFIZER (US) | 2019-11-13 | — | — | EP | disclosed |
| EP-3521292-A1 | BIFUNCTIONAL CYTOTOXIC AGENTS | Pfizer Inc (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3099692-B1 | BIFUNCTIONAL CYTOTOXIC AGENTS | PFIZER (US) | 2019-03-13 | — | — | EP | disclosed |
| US-5659022-A | Oligonucleotide-cyclopropapyrroloindole conjugates as sequence specific hybridization and crosslinking agents for nucleic acids | EPOCH PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |