Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | ABL2 | P42684 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913783 | 0.82 | ADH1A (0.38) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL9382386 | 0.76 | ADH1A (0.42) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16942222 | 0.73 | ADH1A (0.39) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16802230 | 0.72 | LEF1 (0.43) | — | |
| SCHEMBL16946444 | 0.70 | ADH1A (0.37) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16941996 | 0.67 | ADH1A (0.31) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16933119 | 0.67 | ADH1A (0.53) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16941959 | 0.67 | TLR9 (0.34) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7482550 | 0.67 | TLR9 (0.34) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL16933087 | 0.67 | ADH1A (0.39) | ADH1AKITFLT1KDRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659022-A | Oligonucleotide-cyclopropapyrroloindole conjugates as sequence specific hybridization and crosslinking agents for nucleic acids | EPOCH PHARMACEUTICALS, INC. (US) | 1997-08-19 | — | — | US | disclosed |