Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913779 | 1.00 | MAOB (0.50) | MAOBMEN1BCHEKMT2ARAB9A | |
| SCHEMBL8913782 | 1.00 | MAOB (0.50) | MAOBMEN1BCHEKMT2ARAB9A | |
| SCHEMBL8913972 | 0.92 | LMNA (0.55) | MAOBBCHERAB9ASMN1; SMN2TP53 | |
| SCHEMBL8913979 | 0.92 | LMNA (0.55) | MAOBBCHERAB9ASMN1; SMN2TP53 | |
| SCHEMBL8913974 | 0.92 | LMNA (0.55) | MAOBBCHERAB9ASMN1; SMN2TP53 | |
| SCHEMBL8914029 | 0.91 | LMNA (0.53) | MAOBBCHERAB9ASMN1; SMN2TP53 | |
| SCHEMBL8914035 | 0.91 | LMNA (0.53) | MAOBBCHERAB9ASMN1; SMN2TP53 | |
| SCHEMBL8914027 | 0.91 | LMNA (0.53) | MAOBBCHERAB9ASMN1; SMN2TP53 | |
| SCHEMBL8845461 | 0.84 | MAPT (0.56) | MAOBMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8913802 | 0.84 | MAPT (0.56) | MAOBMEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |