Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914027 | 1.00 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8914035 | 1.00 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8913972 | 0.98 | LMNA (0.55) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8913974 | 0.98 | LMNA (0.55) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8913979 | 0.98 | LMNA (0.55) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8913779 | 0.91 | MAOB (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8913782 | 0.91 | MAOB (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8913796 | 0.91 | MAOB (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8845580 | 0.79 | ALDH1A1 (0.56) | GAAMAPTSMN1; SMN2PARP10 | |
| SCHEMBL339813 | 0.78 | LMNA (0.82) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |