Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | GAA | P10253 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | CASP1 | P29466 | 5/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912585 | 0.86 | HDAC3 (0.67) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL5312646 | 0.82 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7797098 | 0.81 | HDAC3 (0.53) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8913128 | 0.80 | HDAC3 (0.52) | EPHX2EPHX1HDAC3HDAC4HDAC1 | |
| SCHEMBL8563145 | 0.78 | EPHX2 (0.51) | EPHX2EPHX1KMT2ACA1CA2 | |
| SCHEMBL14494711 | 0.78 | ALDH1A1 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2127507 | 0.76 | HDAC3 (0.79) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2127498 | 0.76 | HDAC3 (0.79) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14494591 | 0.76 | ALDH1A1 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4501864 | 0.76 | EPHX2 (0.51) | EPHX2EPHX1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633247-A | ANTIARRTHYMIA AGENT | MERCK & CO., INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5206240-A | Antiarrhythmia agents | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |