Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13940986 | 0.91 | LMNA (0.70) | LMNATP53RAB9AKDM4ENPC1 | |
| SCHEMBL8656075 | 0.91 | KDM4E (0.73) | LMNATP53KDM4EHTTHSD17B10 | |
| SCHEMBL9618565 | 0.91 | KDM4E (0.77) | LMNATP53RAB9AKDM4ENPC1 | |
| SCHEMBL14376040 | 0.88 | KDM4E (0.65) | LMNATP53RAB9AKDM4ENPC1 | |
| SCHEMBL7774524 | 0.83 | LMNA (0.72) | LMNATP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7647250 | 0.82 | LMNA (0.74) | LMNATP53RAB9AKDM4ENPC1 | |
| SCHEMBL7774521 | 0.82 | LMNA (0.74) | LMNATP53RAB9AKDM4ENPC1 | |
| SCHEMBL7776284 | 0.81 | MEN1 (0.66) | LMNATP53RAB9AKDM4ENPC1 | |
| SCHEMBL7776317 | 0.79 | MEN1 (0.60) | LMNATP53RAB9AKDM4EHPGD | |
| SCHEMBL5079177 | 0.79 | RAB9A (1.00) | LMNATP53RAB9AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661100-A | HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |