SCHEMBL8914476

SCHEMBL8914476

C=C(COC(=O)NCC(=O)O)S(=O)(=O)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL9177797 0.98 EGLN1 (0.33) EGLN1
SCHEMBL9177792 0.86
SCHEMBL8916896 0.86
SCHEMBL9968041 0.74 ALDH1A1 (0.34)
SCHEMBL8915303 0.74 TYR (0.38)
SCHEMBL9182485 0.73
SCHEMBL7155237 0.73
Glycine SCHEMBL9177787 0.72 GLRA1 (0.31)
SCHEMBL8915197 0.69 KMT2A (0.51)
SCHEMBL4013697 0.66 EGLN1 (0.39) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5637719-A PROTECTING PRIMARY OR SECONDARY AMINE RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-06-10 US disclosed
US-5510491-A 2-PROPENYL CHLOROFORMATE AND DERIVATIVES AS BLOCKING AGENTS FOR AMINO GROUPS OF PEPTIDES DURING PEPTIDE SYNTHESIS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1996-04-23 US disclosed
EP-0401817-B1 Reagents for rapid peptide synthesis RES CORP TECHNOLOGIES INC (US) 1995-09-13 EP disclosed
US-5221754-A Easily removable blocking groups to protect primary or secondary amines RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-06-22 US disclosed
EP-0496836-A4 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS 1993-05-05 EP disclosed
EP-0496836-A1 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS. RES CORP TECHNOLOGIES INC (US) 1992-08-05 EP disclosed
WO-1991005564-A1 SYNTHESIS AND USE OF AMINO ACID FLUORIDES AS PEPTIDE COUPLING REAGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-05-02 WO disclosed
EP-0401817-A2 Reagents for rapid peptide synthesis RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1990-12-12 EP disclosed