⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914476 | 0.86 | EGLN1 (0.34) | — | |
| SCHEMBL9177792 | 0.85 | — | — | |
| Fluoride SCHEMBL9177797 | 0.85 | EGLN1 (0.33) | — | |
| SCHEMBL7155237 | 0.79 | — | — | |
| SCHEMBL9968041 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL9182485 | 0.72 | — | — | |
| SCHEMBL8915197 | 0.71 | KMT2A (0.51) | — | |
| SCHEMBL9129733 | 0.67 | GAA (0.42) | — | |
| SCHEMBL15707348 | 0.65 | TDP1 (0.48) | — | |
| SCHEMBL9185220 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637719-A | PROTECTING PRIMARY OR SECONDARY AMINE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5510491-A | 2-PROPENYL CHLOROFORMATE AND DERIVATIVES AS BLOCKING AGENTS FOR AMINO GROUPS OF PEPTIDES DURING PEPTIDE SYNTHESIS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0401817-B1 | Reagents for rapid peptide synthesis | RES CORP TECHNOLOGIES INC (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5221754-A | Easily removable blocking groups to protect primary or secondary amines | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0401817-A2 | Reagents for rapid peptide synthesis | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-12 | — | — | EP | disclosed |