Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683043 | 0.91 | CYP3A4 (0.35) | CYP3A4TSHRHTR2ASLC6A4IDO1 | |
| SCHEMBL9683058 | 0.87 | TSHR (0.39) | CYP3A4TSHRHTR2ASLC6A4IDO1 | |
| SCHEMBL9192610 | 0.81 | ALDH1A1 (0.37) | CYP3A4TSHRGLAPOLBGAA | |
| SCHEMBL9684753 | 0.81 | CYP3A4 (0.34) | CYP3A4TSHRHTR2ASLC6A4IDO1 | |
| SCHEMBL9683754 | 0.76 | HSD17B10 (0.45) | — | |
| SCHEMBL9504141 | 0.71 | MRGPRX4 (0.46) | TSHRIDO1MRGPRX4POLB | |
| SCHEMBL11316537 | 0.71 | CYP3A4 (0.46) | CYP3A4TSHRHTR2ASLC6A4IDO1 | |
| SCHEMBL9683026 | 0.68 | HSD17B10 (0.43) | — | |
| SCHEMBL2665541 | 0.68 | CYP3A4 (0.52) | CYP3A4TSHRHTR2ASLC6A4SYK | |
| SCHEMBL8393572 | 0.68 | PRKCI (0.45) | CYP3A4TSHRIDO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162583-A | Triazole Herbicide Intermediates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-10 | — | — | US | claimed |
| US-5646291-A | CONTACTING ACETIC ANHYDRIDE, A HIPPURIC ACID, A WATER CONTAINING ACIDIC SOLUTION OF A BENZENEDIAZONIUM SALT AND A NEUTRALIZING AGENT UNDER CYCLOCONDENSATION CONDITIONS | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0493124-B1 | Process for the manufacture of 2-phenyl-4,5-oxazoledione 4-phenylhydrazones | KUREHA CHEMICAL IND CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5162583-A | Triazole Herbicide Intermediates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0493124-A1 | Process for the manufacture of 2-phenyl-4,5-oxazoledione 4-phenylhydrazones | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-07-01 | — | — | EP | disclosed |