Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914522 | 0.87 | CYP3A4 (0.37) | TSHRCYP3A4IDO1MRGPRX4SLC6A4 | |
| SCHEMBL9683043 | 0.84 | CYP3A4 (0.35) | TSHRCYP3A4IDO1MRGPRX4SLC6A4 | |
| SCHEMBL9684753 | 0.83 | CYP3A4 (0.34) | TSHRCYP3A4IDO1ALDH1A1MAPT | |
| SCHEMBL8393572 | 0.80 | PRKCI (0.45) | TSHRCYP3A4IDO1ALDH1A1MAPT | |
| SCHEMBL9683830 | 0.74 | HSD17B10 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11316537 | 0.73 | CYP3A4 (0.46) | TSHRCYP3A4IDO1ALDH1A1MAPT | |
| SCHEMBL2561171 | 0.71 | ALDH1A1 (0.58) | TSHRCYP3A4IDO1ALDH1A1MAPT | |
| SCHEMBL2665541 | 0.70 | CYP3A4 (0.52) | TSHRCYP3A4ALDH1A1MAPTSLC6A4 | |
| SCHEMBL30780916 | 0.69 | MAPT (0.52) | TSHRCYP3A4ALDH1A1MAPTMRGPRX4 | |
| SCHEMBL9507161 | 0.69 | MRGPRX4 (0.51) | TSHRIDO1ALDH1A1MAPTMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162583-A | Triazole Herbicide Intermediates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-10 | — | — | US | claimed |
| US-5162583-A | Triazole Herbicide Intermediates | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-11-10 | — | — | US | disclosed |