Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL8914549

CCOc1ccccn1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MITF O75030 1/20 0.38
PKM P14618 1/20 0.38
MAPT P10636 1/20 0.37
MAPK8 P45983 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HPGD P15428 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL8916452 0.84 GAA (0.41) TSHRALDH1A1LMNATDP1KDM4E
Trifluoroacetic Acid SCHEMBL9571840 0.83 TSHR (0.46) TSHRALDH1A1LMNAKDM4ENPC1
SCHEMBL29968555 0.81
SCHEMBL152133 0.81
Formaldehyde SCHEMBL27984147 0.79 TSHR (0.43) TSHRALDH1A1LMNAKDM4ENPC1
Hydrochloric Acid SCHEMBL8915319 0.79 NPC1 (0.44) TSHRALDH1A1LMNAKDM4ENPC1
SCHEMBL8913703 0.79 ALDH1A1 (0.55) ALDH1A1LMNATDP1KDM4ESMN1; SMN2
Formic Acid SCHEMBL27529182 0.78 TSHR (0.43) TSHRALDH1A1LMNAKDM4ENPC1
Dipyridyl SCHEMBL15796588 0.78 KDM4E (0.56) ALDH1A1LMNATDP1KDM4ENPC1
Trifluoromethanesulfonic Acid SCHEMBL6283511 0.78 LMNA (0.50) TSHRALDH1A1LMNATDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629134-A SOLVENT, ALKALI SOLUBLE RESIN, ACID GENERATOR, PYRIDINE SALT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-05-13 US claimed
US-5220106-A Organic non-quaternary clathrate salts for petroleum separation EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-06-15 US claimed
US-5629134-A SOLVENT, ALKALI SOLUBLE RESIN, ACID GENERATOR, PYRIDINE SALT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-05-13 US disclosed