Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725579 | 0.80 | L3MBTL1 (0.39) | MEN1KMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL11846749 | 0.78 | HIF1A (0.41) | MEN1KMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL1831948 | 0.78 | HIF1A (0.41) | MEN1KMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL10256418 | 0.78 | CHRM3 (0.50) | SLC18A3 | |
| SCHEMBL6926932 | 0.77 | SIGMAR1 (0.46) | MEN1KMT2AALDH1A1HIF1A | |
| SCHEMBL14508514 | 0.76 | MEN1 (0.40) | MEN1KMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL596253 | 0.76 | HIF1A (0.39) | ALDH1A1CHRNB2CHRNA4HIF1A | |
| SCHEMBL3540309 | 0.76 | MEN1 (0.35) | MEN1KMT2ACHRNB2CHRNA4HIF1A | |
| Hydrochloric Acid SCHEMBL10944858 | 0.76 | SIGMAR1 (0.44) | MEN1KMT2AALDH1A1HIF1A | |
| SCHEMBL1702299 | 0.73 | HIF1A (0.37) | MEN1KMT2AALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759917-A1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES, INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |