Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578481 | 0.85 | MAPT (0.39) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL3143334 | 0.81 | KDM4E (0.44) | MAPTPDE10AMEN1KMT2AALDH1A1 | |
| SCHEMBL8876118 | 0.81 | PDE10A (0.44) | MAPTNPSR1PDE10AMEN1KMT2A | |
| SCHEMBL7118784 | 0.80 | KDM4E (0.40) | MAPTNPSR1PDE10AMEN1KMT2A | |
| SCHEMBL30659834 | 0.78 | MAPT (0.40) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10578489 | 0.77 | KMT2A (0.48) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7533773 | 0.75 | LMNA (0.38) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8411907 | 0.73 | KMT2A (0.40) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL8875098 | 0.71 | TP53 (0.46) | MAPTNPSR1PDE10AMEN1KMT2A | |
| SCHEMBL28811993 | 0.70 | KDM4E (0.40) | MAPTNPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298708-A2 | Method for determining thyroxine uptake | Ciba Corning Diagnostics Corp. (US) | 1989-01-11 | — | — | EP | claimed |
| EP-0754178-A1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | Ciba Corning Diagnostics Corp. (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1995027702-A1 | NOVEL FUNCTIONALIZED HYDROPHILIC ACRIDINIUM ESTERS | CIBA CORNING DIAGNOSTICS CORP. (US) | 1995-10-19 | — | — | WO | disclosed |