Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715950 | 0.79 | KMT2A (0.41) | HPGDSMN1; SMN2GAATSHR | |
| SCHEMBL12636857 | 0.79 | MEN1 (0.30) | — | |
| SCHEMBL3721267 | 0.75 | KMT2A (0.36) | HPGDSMN1; SMN2 | |
| SCHEMBL7315465 | 0.75 | GAA (0.51) | HPGDSMN1; SMN2GAATSHR | |
| SCHEMBL24133460 | 0.70 | RIPK2 (0.39) | HPGDSMN1; SMN2 | |
| SCHEMBL2743087 | 0.70 | GAA (0.61) | HPGDSMN1; SMN2GAATSHR | |
| SCHEMBL2743085 | 0.70 | GAA (0.38) | HPGDSMN1; SMN2GAATSHR | |
| Hydrochloric Acid SCHEMBL7310497 | 0.69 | CTSK (0.36) | HPGD | |
| SCHEMBL8308145 | 0.69 | HPGD (0.49) | HPGDSMN1; SMN2GAA | |
| SCHEMBL21806810 | 0.68 | ADORA1 (0.38) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593997-A | 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors | PFIZER INC. (US) | 1997-01-14 | — | — | US | disclosed |