SCHEMBL891486

SCHEMBL891486

[O-][n+]1cc(Cl)cc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30362247 0.97 TSHR (0.41)
SCHEMBL7908598 0.81
SCHEMBL13291157 0.81
SCHEMBL16504663 0.75 GPR84 (0.44)
SCHEMBL2681094 0.73 ALDH1A1 (0.35)
SCHEMBL2680065 0.69
SCHEMBL75106 0.69 ALDH1A1 (0.41)
SCHEMBL2680647 0.67
SCHEMBL6382579 0.67
SCHEMBL844033 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363409-B1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2025-06-11 EP claimed
CN-118724805-B Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-11-01 CN claimed
CN-118724805-A Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-10-01 CN claimed
US-20240308970-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2024-09-19 US claimed
EP-4363409-A1 METHOD FOR PRODUCING ALKYLENE OXIDES Covestro Deutschland AG (DE) 2024-05-08 EP claimed
WO-2023274993-A1 METHOD FOR PRODUCING ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2023-01-05 WO claimed
EP-4112609-A1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES Covestro Deutschland AG (DE) 2023-01-04 EP claimed
US-4287347-A Process for producing 2,3,5-trichloropyridine CIBA-GEIGY CORPORATION (US) 1981-09-01 US claimed
US-20260078131-A1 PYRROLO-PYRIDAZINE INHIBITORS OF JAK2 AJAX THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260028356-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS ABBVIE INC (US) 2026-01-29 US disclosed
EP-4363409-B1 METHOD FOR THE PRODUCTION OF ALKYLENE OXIDES COVESTRO DEUTSCHLAND AG (DE) 2025-06-11 EP disclosed
US-20250066388-A1 1,3,4,7-TETRAHYDRO-2H-PYRROLO[3',2':5,6]PYRIDO[2,3-B][1,4]OXAZEPINE BCL-2 INHIBITORS ABBVIE INC (US) 2025-02-27 US disclosed
CN-118724805-B Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-11-01 CN disclosed
CN-118724805-A Method for preparing pyridine N-oxide in large scale under mild condition 山东仁一生物科技有限责任公司 2024-10-01 CN disclosed
CN-1305471-A Dihydropyrimidines BAYER AG (DE) 2001-07-25 CN disclosed
US-6046207-A FOR INHIBITING ALPHA-1 ADRENORECEPTORS AND TREATING BENIGN PROSTATIC HYPERPLASIA, ALSO CALLED BENIGN PROSTATIC HYPERTROPHY, OR OTHER UROLOGICAL OR GYNECOLOGICAL DISEASES SUCH AS BLADDER OUTLET OBSTRUCTION, NEUROGENIC BLADDER ABBOTT LABORATORIES 2000-04-04 US disclosed
CN-1246861-A Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds ABBOTT LAB (US) 2000-03-08 CN disclosed
EP-0942911-A1 BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS Abbott Laboratories (US) 1999-09-22 EP disclosed
US-5891882-A TREATING BENIGN PROSTATIC HYPERPLASIA OR OTHER UROLOGICAL DISEASES SUCH AS BLADDER OUTLET OBSTRUCTION AND NEUROGENIC BLADDER, OR GYNECOLOGICAL SYNDROMES SUCH AS DYSMENORRHEA ABBOTT LABORATORIES (US) 1999-04-06 US disclosed
WO-1998024791-A1 BENZOPYRANOPYRROLE AND BENZOPYRANOPYRIDINE ALPHA-1 ADRENERGIC COMPOUNDS ABBOTT LABORATORIES (US) 1998-06-11 WO disclosed