Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 4/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27475666 | 0.89 | PPIA (0.52) | PPIAF2PRSS1F10CA12 | |
| SCHEMBL8087931 | 0.88 | PPIA (0.51) | PPIAF2PRSS1F10CA12 | |
| SCHEMBL8912826 | 0.83 | PPIA (0.48) | PPIAF2PRSS1F10CTSL | |
| SCHEMBL13201418 | 0.74 | NPFFR1 (0.44) | PPIACA12CA1CA7CA14 | |
| SCHEMBL8224968 | 0.73 | PPIA (0.45) | PPIAF2PRSS1F10CA12 | |
| SCHEMBL8418697 | 0.73 | PPIA (0.45) | PPIAF2PRSS1F10CA12 | |
| SCHEMBL19559839 | 0.71 | ADRB2 (0.52) | PPIACA12CA1CA7CA14 | |
| SCHEMBL8227060 | 0.70 | PPIA (0.42) | PPIACA12CA1CA7CA14 | |
| SCHEMBL5381278 | 0.70 | PPIA (0.49) | PPIACA12CA1CA7CA14 | |
| SCHEMBL8085796 | 0.70 | PPIA (0.49) | PPIAF2PRSS1F10CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703208-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-30 | — | — | US | disclosed |