Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 14/20 | 0.59 |
| ▸ | MEN1 | O00255 | 13/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919380 | 0.90 | KMT2A (0.48) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8716448 | 0.85 | KMT2A (0.64) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8711149 | 0.81 | KMT2A (0.59) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8663215 | 0.81 | KMT2A (0.59) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8661948 | 0.78 | MEN1 (0.55) | KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6097864 | 0.78 | MEN1 (0.40) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8915225 | 0.76 | KMT2A (0.64) | KMT2AMEN1GAALMNASMN1; SMN2 | |
| SCHEMBL8585347 | 0.75 | KMT2A (0.53) | KMT2AMEN1GAAALDH1A1HTT | |
| SCHEMBL8664720 | 0.74 | MEN1 (0.52) | KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL8711085 | 0.73 | KMT2A (0.51) | KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663363-A | 2-thioxo-imidazolidin-4-one derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-02 | — | — | US | claimed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| US-5663363-A | 2-thioxo-imidazolidin-4-one derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |