Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661948 | 0.82 | MEN1 (0.55) | MEN1KMT2AALDH1A1NPSR1P2RX7 | |
| SCHEMBL8716448 | 0.78 | KMT2A (0.64) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8711085 | 0.77 | KMT2A (0.51) | MEN1KMT2AP2RX7GAA | |
| SCHEMBL8915515 | 0.74 | KMT2A (0.59) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8663215 | 0.74 | KMT2A (0.59) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL8711149 | 0.74 | KMT2A (0.59) | MEN1KMT2AALDH1A1NPSR1GAA | |
| SCHEMBL7159612 | 0.73 | MEN1 (0.47) | MEN1KMT2ATSHRALDH1A1NPSR1 | |
| SCHEMBL8661222 | 0.73 | MEN1 (0.48) | MEN1KMT2AALDH1A1NPSR1P2RX7 | |
| SCHEMBL8479295 | 0.73 | MEN1 (0.55) | MEN1KMT2AALDH1A1P2RX7HTR7 | |
| SCHEMBL7655761 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2ATSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876355-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-11-11 | — | — | EP | claimed |
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | claimed |
| WO-1997019932-A1 | 2-THIOXO-IMIDAZOLIDIN-4-ONE DERIVATIVES AND THEIR USE FOR INCREASING HDL CHOLESTEROL CONCENTRATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-06-05 | — | — | WO | claimed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |