SCHEMBL891570

SCHEMBL891570

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nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.60
ALDH1A1 P00352 8/20 0.55
HPGD P15428 2/20 0.55
CYP19A1 P11511 2/20 0.53
TRPA1 O75762 2/20 0.48
TRPM8 Q7Z2W7 2/20 0.48
TSHR P16473 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
USP2 O75604 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13271704 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL18844821 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL12449336 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL57397 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL17255739 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL23722957 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL57396 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL4256862 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL21250767 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1
SCHEMBL30797343 1.00 EPHX1 (0.60) EPHX1ALDH1A1HPGDCYP19A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
US-20250129312-A1 CONSUMER PRODUCT COMPOSITIONS WITH PERFUME ENCAPSULATES PROCTER & GAMBLE (US) 2025-04-24 US claimed
WO-2025051371-A1 A FRAGRANCE PASTILLE SYMRISE AG (DE) 2025-03-13 WO claimed
WO-2025045354-A1 A FRAGRANCE TABLET SYMRISE AG (DE) 2025-03-06 WO claimed
WO-2025045353-A1 A FRAGRANCE POD SYMRISE AG (DE) 2025-03-06 WO claimed
US-12209232-B2 Consumer product compositions with perfume encapsulates THE PROCTER & GAMBLE COMPANY (US) 2025-01-28 US claimed
CN-119255781-A Antimicrobial mixtures 西姆莱斯股份公司 2025-01-03 CN claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
US-20240358611-A1 COMPOSITIONS SYMRISE AG (DE) 2024-10-31 US claimed
CN-118829416-A Composition (III) 西姆莱斯股份公司 2024-10-22 CN claimed
CN-115551599-A Mint flavor composition 宝洁公司 2022-12-30 CN claimed
CN-115515555-A Mint flavor composition 宝洁公司 2022-12-23 CN claimed
CN-115484922-A Mint flavor composition 宝洁公司 2022-12-16 CN claimed
CN-114513960-A Antimicrobial composition for animal feed 塔明克私人有限公司 2022-05-17 CN claimed
US-11234450-B2 Preparations having a cooling effect SYMRISE AG (DE) 2022-02-01 US claimed
CN-108853105-B Cosmetic composition, pharmaceutical composition and food composition 西姆莱斯股份公司 2021-10-15 CN claimed
CN-107787218-B Liquid cooling composition 西姆莱斯股份公司 2021-07-02 CN claimed
US-20180055069-A1 PREPARATIONS SYMRISE AG (DE) 2018-03-01 US claimed
US-20180049449-A1 PREPARATIONS SYMRISE AG (DE) 2018-02-22 US claimed
EP-1964544-B1 Sensitive skin perfumes TAKASAGO PERFUMERY CO LTD (JP) 2017-07-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11234450-B2 Preparations having a cooling effect CRAT, CPT2, CPT1A EPHX1 2389/4885ALDH1A1 548/4885HPGD 2629/4885
US-20240358611-A1 COMPOSITIONS AZI2, NISCH, CIP2A EPHX1 2269/4885ALDH1A1 815/4885HPGD 3184/4885
US-20180049449-A1 PREPARATIONS CRAT, ACAT2, TAS2R50 EPHX1 1451/4885ALDH1A1 563/4885HPGD 2263/4885
US-20180055069-A1 PREPARATIONS CRAT, ACAT2, TAS2R50 EPHX1 1451/4885ALDH1A1 563/4885HPGD 2263/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 EPHX1 3052/4885ALDH1A1 1377/4885HPGD 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.