Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23767360 | 0.79 | S1PR1 (0.53) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL20746953 | 0.78 | S1PR1 (0.53) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL19275192 | 0.78 | S1PR1 (0.53) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL20858349 | 0.78 | S1PR1 (0.53) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL24179174 | 0.77 | S1PR1 (0.51) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL13290604 | 0.76 | KDM4E (0.35) | — | |
| SCHEMBL20858257 | 0.75 | S1PR1 (0.54) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL16137355 | 0.75 | S1PR1 (0.50) | S1PR1S1PR3S1PR5GNAI3GNAO1 | |
| SCHEMBL1043043 | 0.75 | GNAI3 (0.70) | GNAI3GNAO1GNAI1SIGMAR1 | |
| SCHEMBL250855 | 0.75 | GNAI3 (0.70) | GNAI3GNAO1GNAI1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625046-A | Hydroxyl projecting groups for organic synthesis | KING'S COLLEGE LONDON (GB) | 1997-04-29 | — | — | US | disclosed |
| US-5436331-A | Etherification with N-aryl-4-alkoxy-1,2,5,6-tetrahydropyidine | KINGS COLLEGE LONDON (GB) | 1995-07-25 | — | — | US | disclosed |
| EP-0298982-B1 | PROTECTING GROUPS FOR ORGANIC SYNTHESIS | KING'S COLLEGE LONDON (GB) | 1991-08-28 | — | — | EP | disclosed |