Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.42 |
| ▸ | HTR1A | P08908 | 11/20 | 0.42 |
| ▸ | HTR2A | P28223 | 11/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918028 | 0.87 | DRD2 (0.44) | DRD2HTR1AHTR2ASLC6A4MEN1 | |
| SCHEMBL8917024 | 0.86 | DRD2 (0.41) | DRD2HTR1AHTR2ASLC6A4MEN1 | |
| SCHEMBL8916474 | 0.85 | HTR1A (0.41) | DRD2HTR1AHTR2ASLC6A4 | |
| SCHEMBL8917203 | 0.84 | DRD2 (0.42) | DRD2HTR1AHTR2ASLC6A4MEN1 | |
| SCHEMBL8917726 | 0.84 | DRD2 (0.42) | DRD2HTR1AHTR2ASLC6A4MEN1 | |
| SCHEMBL8918187 | 0.82 | DRD2 (0.39) | DRD2HTR1AHTR2ASLC6A4MEN1 | |
| SCHEMBL8917070 | 0.81 | DRD2 (0.51) | DRD2HTR2ASLC6A4 | |
| SCHEMBL8918049 | 0.81 | DRD2 (0.42) | DRD2HTR1AHTR2ASLC6A4TSHR | |
| SCHEMBL8917179 | 0.79 | DRD2 (0.40) | DRD2HTR1AHTR2ASLC6A4MEN1 | |
| SCHEMBL8916973 | 0.79 | DRD2 (0.40) | DRD2HTR1AHTR2ASLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |